3HP2: Crystal Structure of Human p38alpha complexed with a pyridinone compound

PDB ID: 3HP2Download
MMDB ID: 77039
PDB Deposition Date: 2009/6/3
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 3HP2: monomeric; determined by author and by software (PISA)
Molecular Components in 3HP2
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 14
(Gene symbol: MAPK14)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1H)-one1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1H)-one
2
2
2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303